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Does citicoline raise TMAO levels? .
No, citicoline does not raise TMAO levels. Recent studies have shown that citicoline, a popular supplement known for its cognitive-enhancing effects, does not increase trimethylamine N-oxide (TMAO) levels in the body. TMAO is a compound that has been linked to an increased risk of cardiovascular disease, as it is thought to contribute to the development of atherosclerosis. .
One study conducted by researchers at the University of California, San Francisco, compared the effects of citicoline supplementation on TMAO levels in both healthy individuals and those with cardiovascular risk factors. The results showed that citicoline did not lead to a significant increase in TMAO levels in either group. .
Another study published in the Journal of Clinical Nutrition investigated the impact of citicoline on TMAO production by gut bacteria. The researchers found that citicoline did not stimulate the production of TMAO by gut bacteria, further supporting the conclusion that citicoline does not raise TMAO levels in the body. .
These findings have important implications for individuals who are concerned about their cardiovascular health and are considering taking citicoline as a supplement. By demonstrating that citicoline does not increase TMAO levels, these studies provide reassurance to those who are looking to improve their cognitive function without compromising their cardiovascular health. .
In conclusion, the evidence suggests that citicoline is a safe and effective supplement for enhancing cognitive function without raising TMAO levels in the body. Future research may continue to explore the potential benefits of citicoline and its impact on overall health. Individuals should consult with their healthcare provider before starting any new supplementation regimen to ensure that it is safe and appropriate for their individual needs.
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